Depo-Provera lawsuits are gaining momentum as more women step forward, alleging the birth control shot caused them to develop brain tumors. Known as meningiomas, these tumors can lead to debilitating complications like vision loss, seizures, cognitive issues, and other long-term neurological symptoms.

Chute, O’Malley, Knobloch & Turcy is currently evaluating these cases to determine whether women like you qualify for Depo-Provera brain tumor lawsuits. Call our law firm at 312-775-0042 now to find out if you’re eligible for compensation.
What Illinois Women Need to Know About Depo-Provera and Brain Tumors
Depo-Provera (medroxyprogesterone acetate) is a long-acting hormonal birth control injection manufactured by Pfizer. It’s been widely prescribed since its FDA approval in 1992. However, growing evidence links prolonged use of Depo-Provera to an increased risk of developing intracranial meningiomas, particularly among women who have received multiple injections over several years.
Meningiomas are tumors that form on the membranes surrounding the brain and spinal cord. While most are non-cancerous, their location and size can cause serious health complications, especially if they press against vital brain structures. These tumors can go undetected for years until symptoms become severe.
Depo-Provera Brain Tumor Lawsuits Allege That Pfizer Knew About the Risks
Women in Illinois and throughout the United States are filing Depo-Provera lawsuits alleging that Pfizer failed to adequately warn patients and doctors about these risks, even as internal and external data allegedly pointed to a correlation between Depo-Provera use and brain tumors. The pharmaceutical giant even changed product labels and patient information leaflets in Europe and the UK. to reflect the dangers, but they did not warn women here in the U.S.
The Science Behind Depo-Provera Meningioma Claims
Medical research has identified a significant correlation between prolonged Depo-Provera use and increased risk of meningioma development. Studies dating as far back as 1983 have indicated that the synthetic hormone medroxyprogesterone acetate may stimulate tumor growth, particularly with long-term use.
In March 2024, the British Medical Journal (BMJ) published a study indicating that women who have received the Depo-Provera birth control injection for a prolonged period are 5.6 times more likely to develop brain tumors.
Common Depo-Provera Side Effects and Brain Tumor Symptoms
Alarmingly, Many women who filed Depo-Provera brain tumor lawsuits were diagnosed only after suffering unexplained neurological symptoms, often after years of consistent injections. Identifying the symptoms of meningiomas and getting evaluated by your doctor are the first steps toward your recovery, and getting a settlement from Pfizer.
If you used Depo-Provera and experienced any of the following symptoms, you may have developed a meningioma:
- Severe headaches that worsen over time
- Vision problems, including blurred or double vision
- Seizures or convulsions
- Memory loss and cognitive difficulties
- Hearing loss or ringing in ears
- Balance problems and dizziness
- Weakness in arms or legs
- Speech difficulties
- Personality changes
Depo-Provera Lawsuit Eligibility: Do You Qualify?
Our mass tort attorneys are currently investigating cases involving women who have received birth control injections and later developed meningiomas. The strongest cases involve women who have received the birth control shot for five years or longer. However, if you developed a brain tumor that required surgery or caused severe symptoms after shorter term use, you may still qualify.
You may be eligible for a Depo-Provera lawsuit if you:
- Used Depo-Provera, Depo-SubQ Provera, or a generic equivalent for more than a year
- Were diagnosed with a meningioma (brain tumor)
- Required medical treatment, surgery, or ongoing care
- Experienced lost wages, medical expenses, or pain and suffering
- Have medical records documenting both Depo-Provera use and brain tumor diagnosis
What to Do Next
- See your doctor – If you suspect that you may have developed a meningioma, get evaluated by your doctor right away. Although meningiomas are rarely cancerous, they can cause severe side effects. Your doctor can provide you with a diagnosis, help you manage symptoms, and arrange for further treatment, like surgery if necessary.
- Get your medical records – Make sure to gather any medical records that are linked to your use of the birth control shot, the symptoms you’ve experienced, your diagnosis, and your treatment plan. These records can be used as evidence in your Depo-Provera lawsuit.
- Write down your timeline – Keep track of important events that may impact your case. When did you start using the shot? When did your symptoms begin? When did you first seek medical help for your condition?
- Talk to our attorneys – To find out more about whether you qualify for a lawsuit against Pfizer, we urge you to contact us right away. There is a limited amount of time to file a lawsuit. If you wait too long to take legal action, you will lose your right to recover compensation.
Why File a Depo-Provera Lawsuit?
If you’ve developed a brain tumor or suffered neurological complications after using Depo-Provera, filing a lawsuit may be your best chance to hold the drug manufacturer accountable, and to recover the compensation you need to move forward.
A lawsuit against Pfizer can help you pursue damages for:
- Medical expenses, including imaging, surgery, medications, and long-term care
- Lost wages and diminished earning potential if the tumor has impacted your ability to work
- Pain and suffering, both physical and emotional injuries may be covered
- Future medical treatment, therapy, or home modifications if the condition is disabling
Why Our Lawyers Want to Help
By helping women like you file suit, we stand up for you, your loved ones, and other women who are victims of Pfizer’s negligence, and we put pressure on pharmaceutical companies to prioritize patient safety over their own profits.
Our attorneys believe that pharmaceutical giant Pfizer knew about the link between the birth control shot and brain tumors for decades, and they knew they had a legal responsibility to warn patients and doctors about the risks. Instead, they made the conscious decision to ignore the evidence that demonstrated their product was dangerous. They didn’t pull their birth control from the market, or offer remedies for the women they hurt. They couldn’t even be bothered to add a warning to the product’s labeling in the United States. They simply left millions of women to pay for the harm Depo-Provera caused. We want to help hold them accountable.
Recent Depo-Provera Lawsuit Developments in 2025
The legal landscape surrounding Depo-Provera brain tumor claims has rapidly accelerated throughout 2025, with significant developments that directly impact Illinois women considering legal action.
Explosive Growth in Depo-Provera Case Filings
The number of Depo-Provera lawsuits grew significantly over the past few months, with the multidistrict litigation (MDL) more than doubling in size. As of late May 2025, there were 289 active cases. Lawyers are speaking to an increasing number of women who used Depo-Provera and developed brain tumors, indicating this litigation will continue expanding rapidly.
Multidistrict Litigation (MDL) Formation
A crucial development occurred in early 2025 when courts began consolidating Depo-Provera cases into an MDL in the Northern District of Florida (MDL 3140 IN RE: Depo-Provera (Depot Medroxyprogesterone Acetate) Products Liability Litigation). This consolidation streamlines the legal process and strengthens individual cases.
New Scientific Evidence Linking Depo-Provera to Brain Tumors Emerges
A new peer-reviewed study published in February 2025 has added significant weight to the growing body of evidence linking Depo-Provera to brain tumors. This fresh scientific backing strengthens the foundation for all pending lawsuits and may encourage more women to come forward.
Bellwether Trials Set for Mid-2025
The first bellwether trials in the Depo-Provera litigation are expected to begin in mid-2025. These test cases will provide insight into how juries may respond to the evidence linking Depo-Provera to brain tumors. These initial trials will be critical in determining potential settlement values and litigation strategy.
Enhanced Case Requirements
The court has implemented new procedural requirements to manage the growing caseload. Individuals involved in the case must complete and submit a “Plaintiff Proof of Use/Injury Questionnaire” within 120 days of filing new claims. This ensures thorough documentation of each woman’s experience with Depo-Provera.
Manufacturer Response
Pfizer claims that it decided to change the Depo label to mention the possible tumor risk after it learned of the growing evidence, suggesting the company acknowledges the connection between their product and brain tumors.
These 2025 developments create a more favorable environment for Illinois women seeking justice through Depo-Provera lawsuits, with stronger scientific evidence, streamlined legal processes, and growing momentum in the litigation.
How to File a Depo-Provera Lawsuit
If you or your loved one developed a brain tumor after using the birth control injection, contact our Naperville, Illinois law firm right away for a free consultation to find out if you’re eligible to file a lawsuit. We’ll discuss your use of Depo-Provera, the symptoms you’ve experienced, and how your brain tumor has impacted your life. If you qualify for a lawsuit, our team will go over the evidence you already have, and help you gather additional documentation to support your case. There’s no fee for our experienced attorneys to evaluate your case. If you decide to file a lawsuit, you’ll only pay attorney fees if you win.